Millions of people have alcohol dependence issues to contend with in their day-to-day lives, and it’s a disorder with a raft of associated biological and psychological impacts. Alcohol itself causes changes in our brain chemistry, and this goes some way to explaining why addiction is so prevalent and challenging to cope with. Having a handle on how and why our bodies build up a tolerance and command us to crave alcohol is a good starting point for anyone who wants to begin their own recovery journey.

Automatically Rewarding Consumption
Alcohol causes our brains to release dopamine, which in turn stimulates feelings of pleasure and contentment, hence why we drink it in the first place. But for the satisfaction we feel with each sip, there’s an equal downside, because our brains also forge this link between alcohol and dopamine, which effectively means we end up feeling that it’s fundamentally important to our survival. So, when we drink, our brains reward us, and when we don’t, our brains make us crave alcohol because they’ve been conditioned to do so.
It’s this reward system imbalance that recovery clinics need to address first and foremost. Different practitioners and different countries have their own approaches and treatment paths. People seeking rehab for alcoholics in the UK will find initial support based around CBT and community groups, for instance, whereas in the US it’s more common for medical intervention to be recommended.
A Biological Tolerance
Our brains not only alter our reward systems in response to alcohol, but also attempt to rebalance their chemical makeup as a means of protection from its worse effects. It’s a form of tolerance, and it leads to alcohol having diminishing returns in the effects it has. In other words, addicts need to drink more to get the same effects.
The technical side of this is understandably complex, but alcohol basically amps up gamma-aminobutyric acid (GABA), which has a sedative effect, and our brains respond by cutting production of this neurotransmitter. It also inhibits glutamate, which leaves us thinking more slowly when we drink. Our brains compensate here too, but in the opposite direction. Basically, we end up in a chronic state of imbalance that causes both physical tolerance and severe withdrawal symptoms if drinking stops.

Cravings & Effects
The impact of alcohol on our brain chemistry over long periods of use creates these dependencies and cravings, while also diminishing its effects, which results in a vicious cycle. Over time, it damages the parts of our brain responsible for everything from impulse control to stress response.
Cravings aren’t only triggered by these internal needs and pathways. External cues, including people in our lives and the places we spend time, can kick-start the biological responses that incentivise drinking.
All that’s to say that the damaging impact of alcohol dependency needs to be taken seriously, and that there is lots of support out there for those who decide to reach out for it. Many of the harmful effects can be minimised and even reversed, although the addictive properties have complex roots unique to each person, and that makes tailored treatment a must.
















